Article
Involvement of bovine leukemia virus in induction and inhibition of apoptosis.
Microbes and infection - 1 Jan 2005
Takahashi Masahiko, Tajima Shigeru, Okada Kosuke, Davis William C, Aida Yoko
Abstract excerpt
In a previous study, we identified an interesting mutant form of the Tax protein of bovine leukemia virus (BLV), designated D247G, that has an enhanced capacity to transactivate the long terminal repeat (LTR) of BLV and the cellular proto-oncogene c-fos when compared with wild-type Tax (wt-Tax). We demonstrate here that an infectious strain of BLV containing the mutant D247G form of Tax also differs in its...
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