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Article

A single nucleotide change in the mouse genome accelerates breast cancer progression.

Cancer research - 15 Jan 2010

Seitzer Nina, Mayr Thomas, Streit Sylvia, Ullrich Axel

Abstract excerpt

In the growth factor receptor gene FGFR4 the presence of the common single nucleotide polymorphism Arg388 has been associated with progression of various types of cancer including breast cancer. However, a causative relationship is not readily assigned due to genetic heterogeneity in different patient cohorts. To address this issue, we compared the effects of this allele on malignant progression in the...

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Source

Identifiers

PMID: 20068154
DOI: 10.1158/0008-5472.CAN-09-3239

Genes

FGFR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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