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Article

Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid arthritis.

The Journal of rheumatology - 1 Jan 2002

Fabris Martina, Di Poi Emma, D'Elia Angela, Damante Giuseppe, Sinigaglia Luigi, Ferraccioli Gianfranco

Abstract excerpt

OBJECTIVE: To examine whether severe rheumatoid arthritis (RA) carries a -238 or +489 tumor necrosis factor-alpha (TNF-alpha) genotype different from mild-moderate RA. METHODS: We investigated 163 patients (66 with severe disease) and 67 healthy blood donor controls. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism. RESULTS: Patients with severe RA (all active disease...

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Source

Identifiers

PMID: 11824966

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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