Article
Antibiotic persistence: the role of spontaneous DNA repair response.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2001
Debbia E A, Roveta S, Schito A M, Gualco L, Marchese A
Abstract excerpt
Persisters are a small proportion of a bacterial population that exists in a physiological state permitting survival despite the lethal activity of antibiotics. To explain this phenomenon, it has been suggested that persisters are bacteria repairing spontaneous errors of DNA synthesis. To verify this assumption, Escherichia coli AB1157 and its lexA3 derivative were exposed to a dose 6x MIC of various antibiotics...
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