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The two faces of Janus kinases and their respective STATs in mammary gland development and cancer

1 Jan 2011

Abstract excerpt

Since its discovery as "just another kinase" more than twenty years ago, the family of JAK tyrosine kinases and their respective Signal Transducers and Activators of Transcription (STATs) has been a center of attention in the areas of signal transduction, development, and cancer. The subsequent designation of JAKs as Janus kinases after the mythical two-faced Roman God of the doorways accurately portrays the...

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PMID: 22279417
DOI: 10.4103/1477-3163.90677

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