Article
Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: role in vasculogenic mimicry.
The Prostate - 15 Feb 2002
Sharma Navesh, Seftor Richard E B, Seftor Elisabeth A, Gruman Lynn M, Heidger Paul M, Cohen Michael B, Lubaroff David M, Hendrix Mary J C
Abstract excerpt
BACKGROUND: Tumor cell plasticity represents a significant clinical challenge in that the fate and function of tumor cells can be elusive until a tumor mass is evident. A remarkable example of plasticity is tumor cell vasculogenic mimicry, recently described in aggressive uveal and cutaneous melanoma, in addition to ovarian carcinoma, whereby tumor cells express endothelial-associated genes and form de novo...
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