Article
Microgenomics profile the endogenous angiogenic phenotype in subpopulations of aggressive Melanoma
24 Jul 2008
Abstract excerpt
Beyond the elemental role of blood vessels in tumor growth, fluid conducting networks lacking endothelium (termed vasculogenic mimicry) were identified previously in metastatic melanoma and other cancer types. The etiology remains unclear, though it appears to involve dysregulation of the tumor-specific phenotype and transdifferentiation. Instigating the molecular deciphering of this phenomenon, we established a...
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