Article
Extensive linkage disequilibrium in small human populations in Eurasia.
American journal of human genetics - 1 Mar 2002
Kaessmann Henrik, Zöllner Sebastian, Gustafsson Anna C, Wiebe Victor, Laan Maris, Lundeberg Joakim, Uhlén Mathias, Pääbo Svante
Abstract excerpt
The extent of linkage disequilibrium (LD) was studied in two small food-gathering populations-Evenki and Saami-and two larger food-producing populations-Finns and Swedes-in northern Eurasia. In total, 50 single-nucleotide polymorphisms (SNPs) from five genes were genotyped using real-time pyrophosphate DNA sequencing, whereas 14 microsatellites were genotyped in two X-chromosomal regions. In addition,...
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