Article
Brief communication: patterns of linkage disequilibrium and haplotype diversity at Xq13 in six Native American populations.
American journal of physical anthropology - 1 Jul 2010
Wang Sijia, Bedoya Gabriel, Labuda Damian, Ruiz-Linares Andres
Abstract excerpt
Comparative studies of linkage disequilibrium (LD) can provide insights into human demographic history. Here, we characterize LD in six Native American populations using seven microsatellite markers in Xq13, a region of the genome extensively studied in populations around the world. Native Americans show relatively low diversity and high LD, in agreement with recent genome-wide survey and a scenario of sequential...
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