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Article

Effects of HIV-1 Nef on cellular gene expression profiles.

Journal of biomedical science - 1 Jan 2000

Shaheduzzaman Syed, Krishnan Vyjayanthi, Petrovic Ana, Bittner Michael, Meltzer Paul, Trent Jeffrey, Venkatesan Sundararajan, Zeichner Steven

Abstract excerpt

The early human immunodeficiency virus (HIV) accessory protein Nef makes an important contribution to virulence, but the mechanisms by which Nef influences pathogenesis remain unclear. Many well-studied effects of Nef, like CD4 and class I MHC downregulation, occur posttranslationally. However, Nef has the potential to affect gene expression by interfering with cell signaling pathways and by virtue of structural...

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Share to Oligonucleotide Array Sequence Analysis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11810028
DOI: 10.1007/BF02256581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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