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Article

Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase.

Nucleic acids research - 1 Feb 2002

Kim Eun Mi, Jang Yeun Kyu, Park Sang Dai

Abstract excerpt

Rph1, a Cys2-His2 zinc finger protein, binds to an upstream repressing sequence of the photolyase gene PHR1, and represses its transcription in response to DNA damage in Saccharomyces cerevisiae. In this report, we have demonstrated that the phosphorylation of Rph1 protein was increased in response to DNA damage. The DNA damage-induced phosphorylation of Rph1 was missing in most damage checkpoint mutants...

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Identifiers

PMID: 11809875
DOI: 10.1093/nar/30.3.643
PMCID: PMC100300

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Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase.PMID 11809875Read ↗

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