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Article

Copper and iron disorders of the brain.

Annual review of neuroscience - 1 Jan 2007

Madsen Erik, Gitlin Jonathan D

Abstract excerpt

Copper and iron are transition elements essential for life. These metals are required to maintain the brain's biochemistry such that deficiency or excess of either copper or iron results in central nervous system disease. This review focuses on the inherited disorders in humans that directly affect copper or iron homeostasis in the brain. Elucidation of the molecular genetic basis of these rare disorders has...

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PMID: 17367269
DOI: 10.1146/annurev.neuro.30.051606.094232

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