The toxic milk mouse is a murine model of Wilson disease.

doi:10.1093/hmg/5.10.1619

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Article

The toxic milk mouse is a murine model of Wilson disease.

Human molecular genetics - 1 Oct 1996

Theophilos M B, Cox D W, Mercer J F

Abstract excerpt

Wilson disease (WD) is an autosomal recessive defect of copper transport characterized by massive accumulation of copper in the liver, which can lead to liver failure. Mutations in a copper transporting ATPase (WND or ATP7B) have been shown to cause the disease. The toxic milk mouse mutant (tx) a...

Topics

Adenosine Triphosphatases
Amino Acid Sequence
Animals
Base Sequence
Carrier Proteins
Cation Transport Proteins
Chromosome Mapping
Copper
Copper-Transporting ATPases
DNA, Complementary
Disease Models, Animal
Hepatolenticular Degeneration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Mice

Mice, Mutant Strains

Molecular Sequence Data

Mutation

Rats

Source

Open in PubMed

Identifiers

PMID: 8894697
DOI: 10.1093/hmg/5.10.1619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8894697-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The toxic milk mouse is a murine model of Wilson disease.PMID 8894697Read ↗

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