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Article

Detection of aberrant p16 methylation in the serum of colorectal cancer patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2002

Zou Hong-Zhi, Yu Bao-Ming, Wang Zhi-Wei, Sun Ji-Yuan, Cang Hui, Gao Fei, Li Dong Hua, Zhao Ren, Feng Guo-Guang, Yi Jing

Abstract excerpt

PURPOSE: This study was designed to detect aberrant p16 promoter methylation in the serum of patients with colorectal cancer (CRC) and to explore the possibility of using this assay in early detection or as a prognostic marker of CRC patients. EXPERIMENTAL DESIGN: Methylation-specific PCR was used to detect p16 methylation in DNA extracted from 52 CRCs and matching serum samples and control serum samples from 34...

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PMID: 11801557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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