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Quantitative Detection of Promoter Hypermethylation in Multiple Genes in the Serum of Patients with Colorectal Cancer

23 Sept 2005

Abstract excerpt

OBJECTIVES: While promoter hypermethylation is a common molecular alteration of human colorectal cancer that could be detected in the bloodstream, we tested the feasibility of quantitative detection of aberrant DNA methylation in multiple genes in the serum samples of colorectal cancer patients. METHODS: The pre-therapeutic serum samples of 49 colorectal cancer patients and 41 age-matched controls with normal...

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 16181380
DOI: 10.1111/j.1572-0241.2005.50412.x

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