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Article

p16 protein is upregulated in a stepwise fashion in colorectal adenoma and colorectal carcinoma.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Nov 2016

Al-Ahwal Mahmoud, Gomaa Wafaey, Emam Eman, Qari Yousif, Buhmeida Abdelbaset, Radwi Salman, Al-Maghrabi Basim, Al-Qahtani Mohammad, Al-Maghrabi Jaudah

Abstract excerpt

BACKGROUND/AIMS: p16 is tumor suppressor gene acting as a cell cycle regulator. The present study was conducted to compare p16 expression in normal, dysplastic, and malignant colonic mucosae, and to explore its relation to clinicopathological variables and follow-up data in colorectal carcinoma (CRC). PATIENTS AND METHODS: Tissue microarrays were performed from 25 normal colonic mucosae, 41 colonic adenomas, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

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Share to Proto-Oncogene Proteins p21(ras)

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Source

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Identifiers

PMID: 27976639
DOI: 10.4103/1319-3767.195560
PMCID: PMC5184744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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