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Methylation pattern of ALX4 gene promoter as a potential biomarker for blood-based early detection of colorectal cancer

1 Jan 2015

Abstract excerpt

BACKGROUND: To develop a non-invasive screening method for colorectal cancer, we evaluated the methylation of ALX4 gene promoter in serum samples from patients with colorectal cancer (CRC) and equal number of healthy individuals. MATERIALS AND METHODS: In serum samples from 25 patients with colorectal cancer and 25 healthy control subjects, isolated serum free-floating DNA was treated with sodium bisulfite and...

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PMID: 26918234
DOI: 10.4103/2277-9175.170677

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