Article
Human immunodeficiency virus type 1 (HIV-1) quasispecies at the sites of Mycobacterium tuberculosis infection contribute to systemic HIV-1 heterogeneity.
Journal of virology - 1 Feb 2002
Collins Kalonji R, Quiñones-Mateu Miguel E, Wu Mianda, Luzze Henry, Johnson John L, Hirsch Christina, Toossi Zahra, Arts Eric J
Abstract excerpt
We have recently reported an increased heterogeneity in the human immunodeficiency virus type 1 (HIV-1) envelope gene (env) in HIV-1-infected patients with pulmonary tuberculosis (TB) compared to patients with HIV-1 alone. This increase may be a result of dissemination of lung-derived HIV-1 isolates from sites of Mycobacterium tuberculosis infection and/or the systemic activation of the immune system in response...
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