Article
[Relationship between the Fnu4HI site polymorphism of monoamine oxidase A gene and Parkinson's disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2003
Jiang Xiao-hua, Yang Hui, Yang Jing-fang, Dong Xiu-min, Xu Qun-yuan, Chen Biao
Abstract excerpt
OBJECTIVE: To study the association between the polymorphism of human monoamine oxidase type A (MAO-A) gene and Parkinson's disease(PD). METHODS: Fnu4HI restriction fragment length polymorphism(RFLP) and PCR-RFLP were used to detect the mutation of MAO-A gene. The frequencies of alleles and genotypes at the MAO-A Fnu4HI locus on the X chromosome in different PD group were compared with those of the control group....
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