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[BRCA1 gene mutations in early-onset breast cancer].

Zhonghua yi xue za zhi - 1 Feb 2000

Ding X, Lang J

Abstract excerpt

OBJECTIVE: To detect BRCA1 gene mutations in early-onset breast cancer. METHODS: We use polymerase chain reaction and single strand conformation polymorphism analysis (PCR-SSCP) to examine the mutation at BRCA1 gene exon 2, 11 and 20 in 10 patients with early-onset breast cancer. RESULTS: Mutation was found in one cases (24 years old at diagnosis) at nucleotide 3 732, the substitution of a "G" to a "C" in codon 1...

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Identifiers

PMID: 11798746

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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