Article
[Analysis of BRCA1 gene mutations in patients with early-onset breast cancer and their affected relatives in Guangdong province].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Feb 2009
Zhou Jie, Rao Nan-yan, Li Shun-rong, Jin Liang, Jia Wei-Juan, Gong Chang, Yu Feng-yan, Su Feng-xi, Song Er-wei, Shao Zhi-min
Abstract excerpt
OBJECTIVE: To study the BRCA1 mutations in patients with early-onset breast cancer and their affected relatives in Guangdong province and explore the relationship between BRCA1 mutation and the expressions of estrogen receptor(ER), progesterone receptor(PR), HER2 and ALN. METHODS: From 58 patients with early-onset breast cancer and their affected relatives, the genomic DNA was extracted from the peripheral blood...
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