Article
[Mutation BRCA1 gene in 186 breast cancer patients].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 2001
Lai C, Jiang Z, Song S
Abstract excerpt
OBJECTIVE: To analysis the mutation of BRCA1 gene in 186 breast cancer patients. METHODS: Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and sequential were used in this analysis. RESULTS: 13/186 of patients showed mutation which comprised 7% of the total number of patients. In 8 patients, the mutation was observed in the intron splicing region and in 5 patients, the mutation was...
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