Article
Bayes estimates of haplotype effects.
Genetic epidemiology - 1 Jan 2001
Thomas D C, Morrison J L, Clayton D G
Abstract excerpt
We describe a Markov chain Monte Carlo implementation of a Bayesian approach to estimating associations of a trait with a large set of haplotypes recently introduced by Clayton and Jones [Am J Hum Genet 65:1161-9, 2000]. The model uses the length of the longest segment in common between any two haplotypes to define the prior correlation structure for the set of haplotype effects, using an intrinsic...
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