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Article

A Bayesian approach using covariance of single nucleotide polymorphism data to detect differences in linkage disequilibrium patterns between groups of individuals.

Bioinformatics (Oxford, England) - 15 Aug 2010

Clark Taane G, Campino Susana G, Anastasi Elisa, Auburn Sarah, Teo Yik Y, Small Kerrin, Rockett Kirk A, Kwiatkowski Dominic P, Holmes Christopher C

Abstract excerpt

MOTIVATION: Quantifying differences in linkage disequilibrium (LD) between sub-groups can highlight genetic regions or sites under selection and/or associated with disease, and may have utility in trans-ethnic mapping studies. RESULTS: We present a novel pseudo Bayes factor (PBF) approach that as...

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Identifiers

PMID: 20554688
DOI: 10.1093/bioinformatics/btq327
PMCID: PMC2916719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20554688-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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