Article
Comparison of sib pair-based approaches for identifying quantitative trait loci underlying asthma in the Busselton families.
Genetic epidemiology - 1 Jan 2001
Shugart Y Y, Specchia C, Li H H, Doan B Q, Mathias R A, Devoto M
Abstract excerpt
The goal of this study is to determine the linkage relationship between IgE levels and the 269 microsatellite markers using the Genetic Analysis Workshop 12 Busselton data set. Analyses were carried out using both traditional and new Haseman-Elston methods, the maximum likelihood quantitative trait locus estimation (MLE QTL) method and the nonparametric (NP QTL) method. Our analyses confirmed some of the signals...
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