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Article

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.

The Journal of comparative neurology - 4 Feb 2002

Mufson Elliott J, Ma Shuang Y, Dills John, Cochran Elizabeth J, Leurgans Sue, Wuu Joanne, Bennett David A, Jaffar Syed, Gilmor Michelle L, Levey Alan I, Kordower Jeffrey H

Abstract excerpt

The long-held belief that degeneration of the cholinergic basal forebrain was central to Alzheimer's disease (AD) pathogenesis and occurred early in the disease process has been questioned recently. In this regard, changes in some cholinergic basal forebrain (CBF) markers (e.g. the high affinity trkA receptor) but not others (e.g., cortical choline acetyltransferase [ChAT] activity, the number of ChAT and...

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PMID: 11793352
DOI: 10.1002/cne.10122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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