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Article

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease.

The Journal of comparative neurology - 6 Nov 2000

Mufson E J, Ma S Y, Cochran E J, Bennett D A, Beckett L A, Jaffar S, Saragovi H U, Kordower J H

Abstract excerpt

Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals with mild cognitive impairment (MCI) without dementia from a cohort of people enrolled in the Religious Orders Study. Thirty people (average age 84.7 years) came to...

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Identifiers

PMID: 11042589
DOI: 10.1002/1096-9861(20001106)427:1<19::aid-cne2>3.0.co;2-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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