Article
Comparing the immunogenicity of hepatitis B virus S gene variants by DNA immunization.
Viral immunology - 1 Jan 2001
Wu L, Yuan Z H, Liu F, Waters J A, Wen Y M
Abstract excerpt
DNA immunization was used to compare the immunogenicity of hepatitis B virus S gene variants. Four recombinant plasmid DNAs containing the full-length virus genome with different S gene inserts were used to immunize BALB/c and C57/BL/6 mice. These inserts were cloned from 129L (residue 129, glutamine to leucine), 129H (residue 129, glutamine to histidine) 145R (residue 145, glycine to arginine) variants and the...
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