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Article

Synthetic DNA immunogen encoding hepatitis B core antigen drives immune response in liver.

Cancer gene therapy - 1 Nov 2012

Obeng-Adjei N, Choo D K, Saini J, Yan J, Pankhong P, Parikh A, Chu J S, Weiner D B

Abstract excerpt

The prevalence of hepatitis B virus (HBV) infection in Asia and sub-Sahara Africa is alarming. With quarter of a billion people chronically infected worldwide and at risk of developing liver cancer, the need for a prophylactic or therapeutic vaccination approach that can effectively induce protective responses against the different genotypes of HBV is more important than ever. Such a strategy will require both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23037809
DOI: 10.1038/cgt.2012.61
PMCID: PMC3662808

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