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Article

Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS).

Journal of cell science - 15 Oct 2004

Vanoni Cristina, Massari Silvia, Losa Marco, Carrega Paolo, Perego Carla, Conforti Laura, Pietrini Grazia

Abstract excerpt

It has been suggested that glutamate-induced excitotoxicity plays a central role in the development of motor neuron diseases such as amyotrophic lateral sclerosis (ALS). The GLT-1 isoform of the glutamate transporter gene family is the most important transporter involved in keeping extracellular...

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Identifiers

PMID: 15466883
DOI: 10.1242/jcs.01411

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15466883-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS).PMID 15466883Read ↗

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