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Article

Angptl3 regulates lipid metabolism in mice.

Nature genetics - 1 Feb 2002

Koishi Ryuta, Ando Yosuke, Ono Mitsuru, Shimamura Mitsuru, Yasumo Hiroaki, Fujiwara Toshihiko, Horikoshi Hiroyoshi, Furukawa Hidehiko

Abstract excerpt

The KK obese mouse is moderately obese and has abnormally high levels of plasma insulin (hyperinsulinemia), glucose (hyperglycemia) and lipids (hyperlipidemia). In one strain (KK/San), we observed abnormally low plasma lipid levels (hypolipidemia). This mutant phenotype is inherited recessively as a mendelian trait. Here we report the mapping of the hypolipidemia (hypl) locus to the middle of chromosome 4 and...

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Identifiers

PMID: 11788823
DOI: 10.1038/ng814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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