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Article

Familial combined hypolipidemia: angiopoietin-like protein-3 deficiency

6 Feb 2020

Abstract excerpt

PURPOSE OF REVIEW: Angiopoietin-like protein-3 (ANGPTL3) is emerging as a key player in lipoprotein transport with an expanding role on fatty acid and glucose metabolism. Its deficiency is associated with a favorable metabolic profile. The present review will highlight the recent understanding of metabolic and cardiovascular consequences of ANGPTL3 inactivation by considering both genetic and pharmacological...

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PMID: 32022755
DOI: 10.1097/mol.0000000000000668

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