Article
Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: correlation with clinical disease stages.
Hepatology (Baltimore, Md.) - 1 Jan 2002
Rosen Hugo R, Miner Camette, Sasaki Anna W, Lewinsohn David M, Conrad Andrew J, Bakke Antony, Bouwer H G Archie, Hinrichs David J
Abstract excerpt
Hepatitis C virus (HCV) is the leading cause of chronic hepatitis, affecting approximately 2% of the world's population. The immune mechanisms responsible for the highly variable natural history in a given individual are unknown. We used a multiparameter flow cytometric technique to functionally and phenotypically characterize HCV-specific effector T cells in the peripheral blood of 32 individuals with different...
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