Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice.

Nature genetics - 1 Sept 1999

Harrison K A, Thaler J, Pfaff S L, Gu H, Kehrl J H

Abstract excerpt

In most mammals the pancreas develops from the foregut endoderm as ventral and dorsal buds. These buds fuse and develop into a complex organ composed of endocrine, exocrine and ductal components. This developmental process depends upon an integrated network of transcription factors. Gene targetin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glucagon
Share to Islets of Langerhans
Share to LIM-Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Motor Neurons

Share to Paired Box Transcription Factors

Share to Pancreas

Share to PAX6 Transcription Factor

Share to Somatostatin

Source

Identifiers

PMID: 10471502
DOI: 10.1038/12674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10471502-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice.PMID 10471502Read ↗

Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood.Semantic proximity Read ↗

Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas.Semantic proximity Read ↗

Minireview: transcriptional regulation in pancreatic development.Semantic proximity Read ↗

Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.Semantic proximity Read ↗

Cellular and molecular mechanisms coordinating pancreas developmentSemantic proximity Read ↗

Caudal dysgenesis in Islet-1 transgenic mice.Semantic proximity Read ↗

Human pancreas developmentSemantic proximity Read ↗

Pancreas development in humansSemantic proximity Read ↗

Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8).Semantic proximity Read ↗

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.Semantic proximity Read ↗

Gata6 is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult miceSemantic proximity Read ↗

The endocrine pancreas: insights into development, differentiation, and diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.