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Article

Impaired sensory function in heterozygous P0 knockout mice is associated with nodal changes in sensory nerves.

Journal of neuroscience research - 15 Jan 2002

Samsam M, Frei R, Marziniak M, Martini R, Sommer C

Abstract excerpt

Mice heterozygously deficient in the major myelin component P0 are an established model of an inherited neuropathy and show signs of myelin degeneration in motor nerves. Unlike the case in patients, the sensory nerves are only mildly affected in the mouse mutants and do not show features indicative of myelin degeneration. Unexpectedly, by applying established behavioral tests, we found sensory deficits, as...

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Identifiers

PMID: 11782960
DOI: 10.1002/jnr.10115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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