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Article

Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles

28 Oct 2010

Abstract excerpt

It remains unclear what determines the subcellular localization of hepatitis B virus (HBV) core protein (HBc) and particles. To address this fundamental issue, we have identified four distinct HBc localization signals in the arginine rich domain (ARD) of HBc, using immunofluorescence confocal microscopy and fractionation/Western blot analysis. ARD consists of four tight clustering arginine-rich subdomains. ARD-I...

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PMID: 21060813
DOI: 10.1371/journal.ppat.1001162

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