Article
A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae.
Genetics - 1 Dec 2001
de los Santos T, Loidl J, Larkin B, Hollingsworth N M
Abstract excerpt
The MMS4 gene of Saccharomyces cerevisiae was originally identified due to its sensitivity to MMS in vegetative cells. Subsequent studies have confirmed a role for MMS4 in DNA metabolism of vegetative cells. In addition, mms4 diploids were observed to sporulate poorly. This work demonstrates that the mms4 sporulation defect is due to triggering of the meiotic recombination checkpoint. Genetic, physical, and...
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