The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae.

doi:10.1093/nar/20.3.449

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Article

The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae.

Nucleic acids research - 11 Feb 1992

Leem S H, Ogawa H

Abstract excerpt

The MRE4 gene was cloned by complementation of the defects of meiotic recombination and haploidization in an mre4-1 mutant. Disruption of MRE4 resulted in reduced meiotic recombination and spore inviability. The mre4 spore lethality can be suppressed by spo13, a mutation that causes cells to bypa...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Northern
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Meiosis
Molecular Sequence Data
Mutation
Protein Kinases
Recombination, Genetic
Restriction Mapping
Saccharomyces cerevisiae

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