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Article

Frequency of BRCA1 dysfunction in ovarian cancer.

Journal of the National Cancer Institute - 2 Jan 2002

Geisler John P, Hatterman-Zogg Melanie A, Rathe Jennifer A, Buller Richard E

Abstract excerpt

BACKGROUND: Ovarian cancer is one of the most common hereditary cancers in women. Mutations in the BRCA1 gene increase a woman's risk of ovarian cancer. Testing for BRCA1 mutations is cumbersome and impractical for large populations. Therefore, we developed an efficient strategy to detect various types of BRCA1 dysfunction and also determined the relative frequency of BRCA1 dysfunction in ovarian cancer. METHODS:...

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Share to DNA Methylation
Share to DNA Mutational Analysis
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Loss of Heterozygosity

Share to Ovarian Neoplasms

Share to Polymerase Chain Reaction

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 11773283
DOI: 10.1093/jnci/94.1.61

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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