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Article

Failure of BRCA1 dysfunction to alter ovarian cancer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2002

Buller Richard E, Shahin Mark S, Geisler John P, Zogg Melanie, De Young Barry R, Davis Charles S

Abstract excerpt

PURPOSE: Many factors modify ovarian cancer survival. There are conflicting reports regarding survival of individuals with hereditary BRCA1-related ovarian cancer. None have controlled for other mechanisms of BRCA1 silencing in the control cohort. EXPERIMENTAL DESIGN: Fifty-nine cancers with presumed BRCA1 dysfunction because of mutation (24 germ-line and 16 somatic) or absent BRCA1 mRNA because of promoter...

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Share to BRCA1 Protein
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Neoplasm Staging

Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 12006538

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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