Article
Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease.
The American journal of psychiatry - 1 Jan 2002
Krasuski Jack S, Alexander Gene E, Horwitz Barry, Rapoport Stanley I, Schapiro Mark B
Abstract excerpt
OBJECTIVE: In Down's syndrome (trisomy 21), a dementia syndrome occurs that is phenotypically similar to Alzheimer's disease; the initial phase is characterized by memory loss. The authors used an in vivo structural technique in the predementia stage of Alzheimer's disease in adults with Down's syndrome to investigate whether atrophy of medial temporal lobe structures occurs in these subjects and whether volumes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.