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Article

Progressive myoclonus epilepsy in Down syndrome patients with dementia.

Journal of neurology - 1 Aug 2014

d'Orsi Giuseppe, Specchio Luigi M

Abstract excerpt

This study aimed to elucidate the natural history of senile myoclonic epilepsy, a type of myoclonic epilepsy associated with Alzheimer's disease in adult Down syndrome patients. Twelve Down syndrome patients over the age of 40 years with myoclonic epilepsy and Alzheimer's disease underwent clinical, neuropsychological, neurophysiological, and neuroradiological study. The kariotypes, APOE polymorphisms, all exons...

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Source

Identifiers

PMID: 24893590
DOI: 10.1007/s00415-014-7376-x

Genes

APOE
APP
PSEN1
PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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