Article
Role of AWD/nucleoside diphosphate kinase in Drosophila development.
Journal of bioenergetics and biomembranes - 1 Jun 2000
Timmons L, Shearn A
Abstract excerpt
The abnormal wing discs gene of Drosophila encodes a soluble protein with nucleoside diphosphate kinase activity. This enzymic activity is necessary for the biological function of the abnormal wing discs gene product. Complete loss of function, i.e., null, mutations cause lethality after the larval stage. Most larval organs in such null mutant larvae appear to be normal, but the imaginal discs are small and...
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