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Article

The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations.

Developmental biology - 1 Aug 1993

Timmons L, Hersperger E, Woodhouse E, Xu J, Liu L Z, Shearn A

Abstract excerpt

The abnormal wing discs (awd) gene of Drosophila is homologous to the nm23 gene of mammals, a gene whose expression is altered in metastatic tumors. Both awd and nm23 encode nucleoside diphosphate kinases (NDP kinases). We have examined the accumulation of AWD/NDP kinase during normal development by assaying enzyme activity in extracts. There is a nearly constant level of activity throughout larval and pupal...

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Identifiers

PMID: 8393813
DOI: 10.1006/dbio.1993.1195

Genes

NDP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations.PMID 8393813Read ↗

A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.Semantic proximity Read ↗

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The Impact of Drosophila Awd/NME1/2 Levels on Notch and Wg Signaling Pathways.Semantic proximity Read ↗

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