Article
The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations.
Developmental biology - 1 Aug 1993
Timmons L, Hersperger E, Woodhouse E, Xu J, Liu L Z, Shearn A
Abstract excerpt
The abnormal wing discs (awd) gene of Drosophila is homologous to the nm23 gene of mammals, a gene whose expression is altered in metastatic tumors. Both awd and nm23 encode nucleoside diphosphate kinases (NDP kinases). We have examined the accumulation of AWD/NDP kinase during normal development...
Topics
- Animals
- Brain
- Brain Neoplasms
- Drosophila
- Drosophila Proteins
- Gene Expression
- Insect Hormones
- Lac Operon
- Mutation
- Nucleoside-Diphosphate Kinase
- Transcription, Genetic