Article
Protein kinase D regulates several aspects of development in Drosophila melanogaster.
BMC developmental biology - 25 Jun 2007
Maier Dieter, Nagel Anja C, Gloc Helena, Hausser Angelika, Kugler Sabrina J, Wech Irmgard, Preiss Anette
Abstract excerpt
BACKGROUND: Protein Kinase D (PKD) is an effector of diacylglycerol-regulated signaling pathways. Three isoforms are known in mammals that have been linked to diverse cellular functions including regulation of cell proliferation, differentiation, motility and secretory transport from the trans-Golgi network to the plasma membrane. In Drosophila, there is a single PKD orthologue, whose broad expression implicates...
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