Article
Linkage analysis of human systemic lupus erythematosus-related traits: a principal component approach.
Arthritis and rheumatism - 1 Dec 2001
Rao S, Olson J M, Moser K L, Gray-McGuire C, Bruner G R, Kelly J, Harley J B
Abstract excerpt
OBJECTIVE: To identify chromosomal regions containing genes involved in the susceptibility to human systemic lupus erythematosus (SLE)-related traits. METHODS: In the context of a genome scan, we analyzed 101 SLE-affected sibpairs with respect to dermatologic, renal, immunologic, hematologic, neurologic, cardiopulmonary, and arthritic characteristics. Phenotypes were redefined in terms of principal components,...
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