Article
Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus.
Genes and immunity - 1 Oct 2006
Forabosco P, Gorman J D, Cleveland C, Kelly J A, Fisher S A, Ortmann W A, Johansson C, Johanneson B, Moser K L, Gaffney P M, Tsao B P, Cantor R M, Alarcón-Riquelme M E, Behrens T W, Harley J B, Lewis C M, Criswell L A
Abstract excerpt
A genetic contribution to the development of systemic lupus erythematosus (SLE) is well established. Several genome-wide linkage scans have identified a number of putative susceptibility loci for SLE, some of which have been replicated in independent samples. This study aimed to identify the regions showing the most consistent evidence for linkage by applying the genome scan meta-analysis (GSMA) method. The study...
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