Article
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.
Journal of bacteriology - 1 Jan 2002
Kneidinger Bernd, Marolda Cristina, Graninger Michael, Zamyatina Alla, McArthur Fiona, Kosma Paul, Valvano Miguel A, Messner Paul
Abstract excerpt
The steps involved in the biosynthesis of the ADP-L-glycero-beta-D-manno-heptose (ADP-L-beta-D-heptose) precursor of the inner core lipopolysaccharide (LPS) have not been completely elucidated. In this work, we have purified the enzymes involved in catalyzing the intermediate steps leading to the synthesis of ADP-D-beta-D-heptose and have biochemically characterized the reaction products by high-performance...
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