Article

Pentose Phosphate Pathway Protects <i>E. coli</i> from Antibiotic Lethality

2024-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Disruption of both branches of the canonical pentose phosphate pathway (PPP) in E. coli by combined inactivation of the zwf and talAB genes provokes the restoration of the ancient anabolic variant of PPP (aPPP). In the aPPP, pentose-5-phosphates are synthesized unidirectionally from fructose-6-phosphate and glyceraldehyde-3-phosphate by transketolase B, aldolase A, and phosphatase GlpX, conve...

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Literature Corpus work: d09632e9-0bae-5b03-949e-584e43d1ac2a
DOI: 10.1101/2024.09.07.611820

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