Article
Use of X-chromosome inactivation pattern and laser microdissection to determine the clonal origin of focal nodular hyperplasia of the liver.
Pathology - 1 Jan 2009
Gong Li, Li Yan-Hong, Su Qin, Li Gang, Zhang Wen-Dong, Zhang Wei
Abstract excerpt
AIM: To determine the clonal origin of the whole lesion and each nodule of focal nodular hyperplasia (FNH) and elucidate its nature, simultaneously comparing the clonal composition with hepatocellular adenoma (HA). METHODS: Nine FNHs from eight women, two HAs and four hepatocellular carcinomas (HCCs) were examined by clonality assays based on X-chromosomal inactivation mosaicism in females and laser...
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